Tropical Journal of Pharmaceutical Research

Open Access

Online Manuscript Submission

Submitted Manuscript Trail

Online Payment

Online Subscription

Email Alert

Editor-in-Chief
Professor Augustine O Okhamafe
Email: editor-acc@tjpr.org
Tel: (+234) 0708 315 1651

Editor
Professor Patrick O Erah
Email: editor-reg@tjpr.org [CHAT WITH ME]
Tel: (+234) 0805 526 3622

ISSN: 1596-5996 (p); 1596-9827 (e)
H5-Index (Google Scholar): 20
Thomson Reuters (ISI) IF: 0.569 (2016)
Index Copernicus ICV: 154.63

Indexing & Abstracting

editorial editor email

About this Journal Submit Manuscript Make Payment

The Tropical Journal of Pharmaceutical Research is an Open Access online international journal allowing free unlimited access to abstract and full-text. The journal is devoted to the promotion of pharmaceutical sciences and related disciplines including biotechnology, cell and molecular biology, drug utilization, medical and other life sciences, and related engineering fields. It seeks particularly (but not exclusively) to encourage pharmaceutical and allied research of tropical and international relevance and to foster multidisciplinary research and collaboration among global scientists, the pharmaceutical industry and the healthcare professionals. Although primarily devoted to original research papers, the journal welcomes reviews on current topics of special interest and relevance. All manuscripts are subject to rapid peer review and those of high quality (not previously published and not under consideration for publication in another journal) are published without delay.

Authors who wish to have their manuscripts reviewed by a company that specializes in medical editing and proofreading prior to journal submission, should send their documents to MedScience Editors (http://www.medscienceeditors.com), BioScience Writers (www.biosciencewriters.com) for fast personalized editing services.

Original Research Article: Prospects for intranasal drug delivery systems with Ginkgo biloba in the treatment of cerebral circulatory disorders

N D Bunyatyan, E V Kovtun, I A Samylina, E F Stepanova, Yu V Olefir, L A Korol, A B Prokofiev, V A Evteev, D O Bokov,
http://dx.doi.org/10.4314/tjpr.v18i11.1

Original Research Article: Combination of surfactants with other excipients: Effects on drug release and dimensional changes in matrices

Hassan A Alhmoud, Yazan H Akkam,
http://dx.doi.org/10.4314/tjpr.v18i11.2

Original Research Article: Angelica sinensis polysaccharide promotes apoptosis by inhibiting JAK/STAT pathway in breast cancer cells

Zhaoyuan Fu, Yingdong Li, Suisheng Yang, Chengxu Ma, Rongrong Zhao, Huan Guo, Huiping Wei,
http://dx.doi.org/10.4314/tjpr.v18i11.3

Original Research Article: Protective effect of valproic acid on MPP+-induced neurotoxicity in dopaminergic SH-SY5Y cells through Cdk5/p35/Erk signaling cascade

Jakkapong Muangsab, Peerada Prommeenate, Banthit Chetsawang, Pennapa Chonpathompikunlert, Wanida Sukketsiri, Pilaiwanwadee Hutamekalin,
http://dx.doi.org/10.4314/tjpr.v18i11.4

Original Research Article: Polydatin ameliorates renal fibrosis in a streptozotocinâ€“induced rat model of diabetic nephropathy by inhibiting TLR4/NF-κB signaling

Huimin Niu, Gang Li, Yanhong Qiao, Feng Wang,
http://dx.doi.org/10.4314/tjpr.v18i11.5

..... Show/hide more

Original Research Article: Luteolin attenuates high glucose-induced cytotoxicity by suppressing TXNIP expression in neuronal cells

Tuerhong Tuerxun, Xiaopeng Li, Long Ma, Yi Wang, Bo Liu, Xiangyou Yu,
http://dx.doi.org/10.4314/tjpr.v18i11.6

Original Research Article: Molecular generation and characterization of an efficient recombinant vaccine for avian influenza A/H5N8 in Saudi Arabia

Thamer AF Boubk, Jamal SM Sabir, Salah EM Abo-Aba, Mernan J Sabir, Nahid H Hajrah, Alawiah M Alhibshi, Mohamed Abu-Zeid, Abdelfatteh EI Omri, Mumdooh J Sabir, Ehab H Mattar, Mohamed A Ali, Irfan A Rather, Majid R Kamli,
http://dx.doi.org/10.4314/tjpr.v18i11.7

Original Research Article: Osthole represses growth of multiple myeloma cells by regulating PI3K/AKT and ERK pathways

Lingling Huang, Xiaofeng Zhao, Zhengmei He, Lizhong Guo,
http://dx.doi.org/10.4314/tjpr.v18i11.8

Original Research Article: Curcumin suppresses leukemia cell proliferation by down-regulation of P13K/AKT/mTOR signalling pathway

Guo Ting, Wu Jin, Ding Ting, Wang Hongxiang, Xu Liwen, Yao Xiaodan,
http://dx.doi.org/10.4314/tjpr.v18i11.9

Original Research Article: MiR-646 targets PDK1 to recede aerobic glycolysis and cell proliferation in nasopharyngeal carcinoma

Kaiquan Zhu, Renyu Lin, Aidan Xiaguang,
http://dx.doi.org/10.4314/tjpr.v18i11.10

Original Research Article: Design of dual inhibitors of human TNF-α and IL-6 with potentials for the treatment of rheumatoid arthritis

Shu-Qiang Wang, Meng Shi, Lei Fang, Sheneg-Ming Xu, Cong Wang, Zhong-Xiang Yu,
http://dx.doi.org/10.4314/tjpr.v18i11.11

Original Research Article: Indomethacin inhibits PGE2, regulates inflammatory response, participates in adipogenesis regulation, and improves success rate of fat transplantation in C57/B6 mice

Hongyu Xue, Hongyi Zhao, Huiying Wang, Song Zhang,
http://dx.doi.org/10.4314/tjpr.v18i11.12

Original Research Article: Duloxetine alleviates high light-induced anxiety-related behaviors in Wistar rats

Hasan Çalıskan, Koray Hamza Cihan, Emel Günes, Ahmet Ergün, Mitat Can Öztürk, Sükrü Hakan Gençer, Süleyman Kılınç, Zakir Osmanov, Mehmet Oguzhan Kaya, Murat Kılıçdagi,
http://dx.doi.org/10.4314/tjpr.v18i11.13

Original Research Article: Effect of sinomenine on proliferation and apoptosis of oral squamous cell carcinoma cells, and its underlying mechanism of action

Tao Geng, Wei Cheng, Le Ren, Daxu Li, Ran Xu, Zhe Zhang, Rui Wang,
http://dx.doi.org/10.4314/tjpr.v18i11.14

Original Research Article: Azadiradione exerts anti-inflammatory and anti-oxidant effects, alleviates dopaminergic neurodegeneration and reduces ^5;-synuclein levels in MPTP-induced mouse model of Parkinson disease

Tao Jin, Xuemei Cao, Zongwen Gao, Xue-Qin Yan,
http://dx.doi.org/10.4314/tjpr.v18i11.15

Original Research Article: Evaluation of in vitro cytotoxicity effect of Clinacanthus nutans (Brum. f.) Lindau standardized leaf extracts

Kameh Esmailli, Armaghan Shafaei, Abdalrahim FA Aisha, Fouad Saleih R Al-Suede, Amin Malik Shah Abdul Majid, Zhari Ismail,
http://dx.doi.org/10.4314/tjpr.v18i11.16

Original Research Article: Effect of Nuangong zhitong decoction on primary dysmenorrhea in mice

Ya-Zhen Xie, Jian-Qiang Qian, Qi-Bin Lu,
http://dx.doi.org/10.4314/tjpr.v18i11.17

Original Research Article: Curcumin inhibits gastric cancer growth via down-regulation of zinc finger protein, ZNF139

Heng Xu, Wenhui Yu, Wenbo Yu, Meijun Zhang, Yingying Ma, Duoxiang Wu, Qifan Zhang,
http://dx.doi.org/10.4314/tjpr.v18i11.18

Original Research Article: Mechanism of hesperidin-induced apoptosis in human gastric cancer AGS cells

Wangmei Yu, Xiaolong Xie, Zheke Yu, Qingzheng Jin, Huizhong Wu,
http://dx.doi.org/10.4314/tjpr.v18i11.19

Original Research Article: Hepatoprotective and antioxidant properties of the methanol leaf extract of Diaphananthe bidens in acetaminophen-induced hepatotoxicity in rats

Patrick E Aba, Kenneth O Ugwueze, Samuel O Onoja, Christian O Okorie-Kanu, Aruh O Anaga,
http://dx.doi.org/10.4314/tjpr.v18i11.20

Original Research Article: Cytotoxic activity of lithospermum erythrorhizon root extract against childhood acute leukemia cells via regulation of PI3K/AKT/mTOR pathway

Zhongxia Fu, Li Wang, Wei Zhang, Jingjing Wang, Shengdong Zhu, Wei Deng,
http://dx.doi.org/10.4314/tjpr.v18i11.21

Original Research Article: Skin care benefits of bioactive compounds isolated from Zanthoxylum piperitum DC. (Rutaceae)

Sung Chun Kim, Mi Yeon Moon, Ha Youn Lee, Jungha Kim, Moon Sik Chang, Joonseok Cha,
http://dx.doi.org/10.4314/tjpr.v18i11.22

Original Research Article: Effectiveness of different resuscitation methods for severe uncontrolled hemorrhagic shock in a dog model

Shan Jiang, Shaoming He, Yang Sun,
http://dx.doi.org/10.4314/tjpr.v18i11.23

Original Research Article: Number of osteoclasts, receptor activator of nuclear factor kappa-b ligand and osteoprotegerin expression in electrolyzed reduced water-treated orthodontic tooth movement in Wistar rats

Ananda Firman Putranto, Retno Indrawati Roestamadji, Rini Devijanti Ridwan, Ida Bagus Narmada,
http://dx.doi.org/10.4314/tjpr.v18i11.24

Original Research Article: Studies on the toxicokinetics of intragastrically-administered paracetamol, aminophenazone, caffeine and chlorphenamine maleate tablets in rats

Wei Sun, Shenghua Gu, Xin Zhang, Jinyao Lu, Yingmin Gu, Yiwen Huang, Guifeng Xu, Jiajun Xie,
http://dx.doi.org/10.4314/tjpr.v18i11.25

Original Research Article: Effect of Acorus tatarinowii extract on hyperprolactinemia in rats

Hong Zheng, Fu-tao Zhang, Hong-mei Tang, Jin-zhao Zhao, Xian-jun Meng, Wan-jing Sun,
http://dx.doi.org/10.4314/tjpr.v18i11.26

Original Research Article: Simple and sensitive chromatographic method development for in-vitro and in-vivo analysis of doxorubicin-loaded poly lactic-co-glycolic acid nanoparticles

Sumaira Irum Khan, Zafar Iqbal, Fazli Nasir, Muhammad Ismail, Naila Shahbaz, Asma Khan, Muzna Ali Khattak, Mirina Sakhi,
http://dx.doi.org/10.4314/tjpr.v18i11.27

Original Research Article: Assessment of patients knowledge of tuberculosis and its impact on self-management ability

Ameen M Almohammadi, Dina S Qurashi, Ghaydaa A Abuouf,
http://dx.doi.org/10.4314/tjpr.v18i11.28

Original Research Article: Antimalaria therapy and changes in oxidative stress indices in falciparum malaria infection in Calabar metropolis, Nigeria

Augusta C Nsonwu-Anyanwu, Uloma O Osuoha, Magnus C Nsonwu, Chinyere AO Usoro,
http://dx.doi.org/10.4314/tjpr.v18i11.29

Original Research Article: Regional versus general anesthesia for different categories of caesarean deliveries amongst Chinese women: A retrospective cohort analysis

Li Xu, Hao Zhang, Xiaoguang Li,
http://dx.doi.org/10.4314/tjpr.v18i11.30

Original Research Article: Clinical efficacy and safety of xiaoyao pill in post-stroke depression: A systematic review and meta-analysis of randomized controlled trials

Yue Xu, Qing Zhang, Fang Yang, Suoguo Jing, Xiangning Zhang, Xuemei Qiu, Weiyin Chen,
http://dx.doi.org/10.4314/tjpr.v18i11.31

Review Article: Recent perspectives on chemosensitizing effects of Astragalus membranaceus-derived components: A mini review

Gihyun Lee, Kang-Hyun Leem, Wonnam Kim,
http://dx.doi.org/10.4314/tjpr.v18i11.32

Review Article: Natural plant polyphenols for alleviating oxidative damage in man: Current status and future perspectives 5495 views

Jiao-Kun Li, Xue-Duan Liu, Li Shen, Wei-Min Zeng, Guan-Zhou Qiu,
http://dx.doi.org/10.4314/tjpr.v15i5.27

Original Research Article: Development and optimization of fluoxetine orally disintegrating tablets using Box-Behnken design 5370 views

Bahaa E Ali, Abdullah K Rabba, Mohamed H Fayed, Khalid M El-Say, Mohammad Khalid Anwer, Mohammad Javed Ansari, Ramadan Al-Shdefat, Gamal A Gabr,
http://dx.doi.org/10.4314/tjpr.v15i4.1

Original Research Article: Targeting integrin-ß1 impedes cytokine-induced osteoclast differentiation: a potential pharmacological intervention in pathological osteolysis 4945 views

Xing Lu, Xing-Lin Zhang, Kai Chu, Guo-Dong Zhang, Yan-Ping Zheng,
http://dx.doi.org/10.4314/tjpr.v15i2.11

Original Research Article: Physicochemical characterization of inclusion complex of catechin and glucosyl-ß-cyclodextrin 4834 views

Bin Li, Wenbo Zhang, Hanjun Ma,
http://dx.doi.org/10.4314/tjpr.v15i1.23

Original Research Article: Effect of β-adrenoceptor on cardiac fibrosis in rat cardiac fibroblast cells and its potential mechanism 4622 views

Yuan Zhang, Hui Zhang, Yitong Ma, Yining Yang, Miaomiao Ma, Xiaoli Zhu, Li Wang,
http://dx.doi.org/10.4314/tjpr.v15i4.7

Original Research Article: Chinese herbal medicines â€“ Comparison of doses prescribed in clinical practice and those in China pharmacopeia 4224 views

Sheng-Lou Ni, Chuan-Rong Chen, Yan-Ling Fu, Lin Zhang, Jia Song,
http://dx.doi.org/10.4314/tjpr.v14i1.24

Original Research Article: Enhancement of aqueous solubility and oral bioavailability of nelfinavir by complexation with ß-cyclodextrin 4168 views

Shilpi Kumari, Ganesh T Bhawar, Prashant B Musmade, Shaila Lewis,
http://dx.doi.org/10.4314/tjpr.v14i8.3

Original Research Article: Effect of inulin supplementation in male mice fed with high fat diet on biochemical profile and α-amylase gene expression 3879 views

Zahra Pouyamanesh, Mahsa M Amoli, Parichehreh Yaghmaei, Azadeh Ebrahim-Habibi,
http://dx.doi.org/10.4314/tjpr.v15i6.12

Review Article: Coordination compounds of M(II) biometal Ions with acid-type anti-inflammatory drugs as ligands â€“ A review 3748 views

Nenad S Krstic, Ruzica S Nikolic, Maja N Stankovic, Nada G Nikolic, Dragan M Doraevic,
http://dx.doi.org/10.4314/tjpr.v14i2.21

Original Research Article: Synthesis and antibacterial profile of novel azomethine derivatives of β-phenylacrolein moiety 3403 views

Sridevi Chigurupati, Neeraj Kumar Fuloria, Shivkanya Fuloria, Sundram Karupiah, Ravichandran Veerasamy, Appala Raju Nemala, Lim Jun Yi, Ang xiang Ilan, Syed Adnan Ali Shah,
http://dx.doi.org/10.4314/tjpr.v15i4.22

November 2019; Volume 18, Issue 11
October 2019; Volume 18, Issue 10
September 2019; Volume 18, Issue 9
August 2019; Volume 18, Issue 8
July 2019; Volume 18, Issue 7
June 2019; Volume 18, Issue 6
May 2019; Volume 18, Issue 5
April 2019; Volume 18, Issue 4
March 2019; Volume 18, Issue 3
f 2019; Volume 18, Issue 2
February 2019; Volume 18, Issue 2
January 2019; Volume 18, Issue 1