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Review Article | OPEN ACCESS

An overview of cholera outbreak in Nigeria - consequences and possible solutions

Chukwunonso Patrick Eya1, 2 , Nichodemus Amaechi Eze1, Ogunbola Omolabake Ogunfolakan1, Chidera Confidence Agu1, Onyinyechi Victoria Amadi1, Adenike Anastasia Akanni1, Izuchukwu Emmanuel Eya3

1Department of Medical Laboratory Science, College of Medicine and Health Science, Afe Babalola University, Ado-Ekiti, Ekiti State; 2Department of Environmental Health Science, Faculty of Health Science, National Open University of Nigeria, Cadastral Zone, Nnamdi Azikiwe Expressway, Jabi, Abuja; 3Department of Medicine and Surgery, School of Clinical Sciences, Babcock University, Ilishan-Remo, Ogun State, Nigeria.

For correspondence:-  Chukwunonso Eya   Email: pceya@noun.edu.ng   Tel:+234-8138476175

Received: 4 March 2025        Accepted: 11 October 2025        Published: 31 October 2025

Citation: Eya CP, Eze NA, Ogunfolakan OO, Agu CC, Amadi OV, Akanni AA, et al. An overview of cholera outbreak in Nigeria - consequences and possible solutions. Trop J Pharm Res 2025; 24(10):1313-1325 doi: https://dx.doi.org/10.4314/tjpr.v24i10.12

© 2025 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..

Abstract

Cholera is acute diarrheal disease caused by Vibrio cholerae bacterium, primarily transmitted through contaminated water and food. Nigeria has experienced recurrent cholera outbreaks, with significant public health, social, and economic impacts. This review examines the causes, responses, and challenges related to cholera outbreaks, along with potential solutions. The primary cause of cholera in Nigeria is inadequate access to clean water, poor sanitation, and improper waste disposal, leading to contamination of water sources. The disease affects areas with limited healthcare infrastructure and low hygienic standards. Despite efforts by the Nigerian government and foreign organizations to eradicate cholera, outbreaks persist, typically worsened by growing urbanization, seasonal flooding, and conflicts that impede healthcare delivery. The response to cholera outbreaks in Nigeria has included emergency vaccination campaigns, improved water treatment programs, and public health education. However, these efforts face significant obstacles, such as inadequate funding, lack of coordinated action between government agencies, and the persistence of unsafe water sources. To mitigate cholera’s impact, this review suggests several solutions, including improving access to clean water, enhancing sanitation infrastructure, and strengthening surveillance and early warning systems. Collaboration involving government, international organizations, and local communities is essential for preventing future outbreaks of cholera in Nigeria.

Keywords: Cholera, Outbreak, Causes, Impact, Challenges, Solutions, Nigeria

Impact Factor
Thompson Reuters (ISI): 0.6 (2023)
H-5 index (Google Scholar): 49 (2023)

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