Gholamreza Assadnassab1 
,
Shahram Dabiri Oskoei2
For correspondence:- Gholamreza Assadnassab Email: assadnassabgh@iaut.ac.ir Tel:+989144121145
Received: 4 March 2015 Accepted: 28 July 2015 Published: 29 September 2015
Citation: Assadnassab G, Oskoei SD. Application of 99mTc-DTPA radiotracer in Persian cat renal scintigraphy. Trop J Pharm Res 2015; 14(9):1691-1694 doi: 10.4314/tjpr.v14i9.21
© 2015 The authors.
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Purpose: To evaluate the suitability of 99mTc-DTPA as a radiotracer in Persian cat's renal scintigraphy.
Methods: twelve adult healthy Persian cats were selected. For scintigraphy, the animals were anesthetized and 99mTC-DTPA was injected via the femoral vein as a bolus at a dose of 1.5 mCi. Immediately after intravenous injection of radiotracer, scintigraphic operation was conducted on the renal organ. dministration of the radioisotope and accumulation of radioisotope in the tissues was monitored by specific imaging theemanating
Results: Distinct scintigraphic scans were obtained using 99mTC-DTPA. Visual comparison of the scans indicates that there was no significant difference in the accumulation of radiotracer. In dynamic scans, symmetric and concurrent distribution of 99mTc-DTPA in the kidney was observed.
Conclusion: The results show that the radiopharmaceutical 99mTc-DTPA is suitable for use in Persian cat's renal scintigraphy, and this makes it potentially useful in research and clinical practice.
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