Roongtawan Supabphol1,
Janpen Tangjitjareonkun2
1Department of Physiology, Faculty of Medicine, Srinakharinwirot University, Bangkok 10110;
2Department of Basic Science and Physical Education, Faculty of Science at Si Racha, Kasetsart University, Si Racha Campus, Chonburi 20230, Thailand.
For correspondence:- Janpen Tangjitjareonkun
Email: xjanpen@yahoo.com
Received: 9 December 2013
Accepted: 20 October 2014
Published: 15 December 2014
Citation:
Supabphol R, Tangjitjareonkun J.
Chemical Constituents and Biological Activities of Zanthoxylum limonella (Rutaceae): A Review. Trop J Pharm Res 2014; 13(12):2119-2130
doi:
10.4314/tjpr.v13i12.25
© 2014 The authors.
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Abstract
Zanthoxylum limonella belongs to the family of aromatic deciduous trees and shrubs, Rutaceae. In traditional medicine practice, various parts of Z. limonella are used for the treatment of dental caries, febrifugal, sudorific, rheumatism, diuretic, stomach ache and diarrhea. Secondary metabolites have been isolated the stems, stem barks, and fruits. The plant contains alkaloid, amide, lignin, coumarin and terpenoid compounds. The extracts of the various parts, essential oil from the fruits and some pure compounds of Z. limonella have been found to have biological activities, for example, mosquito repellent and mosquito larvicidal, antimicrobial, antioxidant, and antitumour properties. This review compiles some scientific information on botanical description, traditional uses, phytochemical constituents and biological activities of Z. limonella.
Keywords: Zanthoxylum limonella, Chemical constituents, Biological activities, Antimicrobial, Antioxidant, Antitumour