Phuong Dong Tran Nguyen1,
Nguyen Binh Truong2,
Thuan Duc Lao1
1Department of Pharmaceutical and Medical Biotechnology, Faculty of Biotechnology, Ho Chi Minh City Open University, Ho Chi Minh City, Vietnam;
2Faculty of Biology, Dalat University, Dalat, Lam Dong, Vietnam.
For correspondence:- Thuan Lao
Email: thuan.ld@ou.edu.vn
Accepted: 24 November 2023
Published: 31 December 2023
Citation:
Nguyen PD, Truong NB, Lao TD.
Hypoglycemic and glucose-lowering properties of Cordyceps militaris. Trop J Pharm Res 2023; 22(12):2561-2566
doi:
10.4314/tjpr.v22i12.20
© 2023 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..
Abstract
Diabetes mellitus is a serious endocrine disease characterized by hyperglycemia. This disease has been regarded as a major global health issue. Although majority of the current therapeutic approaches are beneficial in treating diabetes, there are still unfavorable side effects. The Chinese traditional medicinal fungi, Cordyceps militaris, has been used in the treatment of diabetes mellitus for centuries. This study summarizes the chemical compounds in Cordyceps militaris and their corresponding hypoglycemic effect in the development of therapeutic agents for diabetes mellitus based on recent reports. Several studies using chemically induced diabetic rats and mice models have established the antidiabetic effect of Cordyceps militaris administered at various doses. This report reveals that Cordyceps militaris has a great deal of promise and should be taken into consideration for the development of novel antidiabetic therapies.
Keywords: Cordyceps militaris, Diabetes mellitus, Anti-diabetes, Hypoglycemic activity