Bin Chen1 
,
JiFeng Xie2,
KeKe Ding2,
ChunRong Gong2
For correspondence:- Bin Chen Email: sshchenbin@163.com
Accepted: 29 August 2023 Published: 30 September 2023
Citation: Chen B, Xie J, Ding K, Gong C. Osmidrosis lotion affect ApoD and ABCC11 mRNA levels in axillary osmidrosis patients. Trop J Pharm Res 2023; 22(9):1887-1891 doi: 10.4314/tjpr.v22i9.16
© 2023 The authors.
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Purpose: To investigate the potential role of osmidrosis lotion in alleviating axillary osmidrosis (AO).
Methods: Forty patients were randomly divided into four groups (n = 10). Patients were treated via topical application of Lithargyrum, Sophora flavescens Alt., or Cortex dictamni, or osmidrosis lotion, for 40 min over a three-month period. Total skin RNA was extracted from samples using TRIzol while total platelet RNA was treated with DNase I, followed by quantification using NanoDrop and Agilent 2100 Bioanalyzer.
Results: Lithargyrum, Sophora flavescens Alt. and Cortex dictamni significantly inhibited the mRNA ex
Conclusion: The suppressive effect of these natural remedies may be beneficial in the development of non-surgical therapy for AO and therefore would be worth further investigation.
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