Faisal M Awadh¹, Hassan AS Yousef^1,2 , Anwar AM Abdu³, Fawze Alnadari⁴, Tameem AAA Shareef¹, Roqaia AHH Salam⁵, Zakarya AA Abdullah⁶, Ammar AA Ebrahim¹, Adel MAZ Wahan¹, Maged YM Sabri⁷, Abdulmajid AA Ali¹

¹Department of Medical Laboratory, College of Medicine and Health Sciences, Hodiedah Univerity, Hodiedah, Yemen; ²Key Laboratory of Biorheological Science and Technology, Ministry of Education, Chongqing University, Chongqing 400044, China; ³Faculty of Laboratory Medicine, Jiblah University for Medical and Health Sciences, Ibb, Yemen; ⁴Functional Protein Laboratory, Research and Development Center, Jiangsu Tianmeijian Nature Bioengineering Co., Ltd., Nanjing 210046, China,; ⁵Department of Medical Laboratory Sciences, Faculty of Medicine and Health Sciences, Ibb University, Ibb, Yemen; ⁶Clinical Laboratory Diagnostic, Key Laboratory of Clinical Laboratory Diagnostics, School of Laboratory Medicine, Chongqing Medical University, Chongqing 400016, China; ⁷Blood Bank Center Of Authority Al-Thawra General Hospital Hodeidah, Hodiedah, Yemen.

For correspondence:-  Hassan Yousef   Email: hassan2sulaiman@gmail.com

Received: 4 February 2026        Accepted: 18 May 2026        Published: 31 May 2026

Citation: Awadh FM, Yousef HA, Abdu AA, Alnadari F, Shareef TA, Salam RA, et al. Prevalence of transfusion-transmitted infections among blood donors in Hodiedah City, West Yemen. Trop J Pharm Res 2026; 25(5):733-739 doi: https://dx.doi.org/10.4314/tjpr.v25i5.15

© 2026 The authors.
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Abstract

Purpose: To investigate the prevalence of Human Immunodeficiency Virus (HIV), Hepatitis B virus (HBV), Hepatitis C virus (HCV), and Syphilis among blood donors at the National Blood Transfusion and Research Center in Hodiedah, Yemen. Method: This was a retrospective study to analyze confirmatory test results for HBV, HCV, HIV, and syphilis among blood donor data from January 1, 2014, to December 31, 2015. Socio-demographic data and risk variables were gathered using a standardized questionnaire. Data was presented in frequency and percentages and compared using Chi-square test. P < 0.05 was considered significant. Results: From a total of 23,010 blood donors, a remarkable 22,896 (99.5 %) were male, while just 28 (0.5 %) were female. Furthermore, 240 (1.04 %) were infected, and 6 (0.03 %) were identified as having multiple illnesses (co-infections of HBV and syphilis). Prevalence rates of HBV, HCV, HIV, and Syphilis were 0.56 %, 0.12 %, 0.07 %, and 0.30 %, respectively. Conclusion: There has been a significant rise in the number of individuals testing positive for HIV over the duration of the study. Although the overall prevalence of transfusion-transmitted diseases (TTIs) was negligible, it was imperative to conduct thorough screening of all blood units to guarantee the safety of transfusions.

Keywords: Transfusion-transmissible infections (TTIs), Hepatitis B virus, Hepatitis C virus, Human immunodeficiency virus, Syphilis, Treponema pallidum

Impact Factor
Thompson Reuters (ISI): 0.6 (2023)
H-5 index (Google Scholar): 49 (2023)