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Original Research Article | OPEN ACCESS

Sodium, potassium and calcium ions in diabetic patients' serum and their correlation with glycaemic control in Jordanian patients: A cross-sectional study

Maissa T Shawagfeh1 , Munir T Shawagfeh2, Israa F Yousef3

1Al- Balqa Applied University, Zarqa University College, Department of Allied Medical Sciences,; 2Anesthesiology and Pain Management, King Hussein Cancer Centre, Amman,; 3Allied Medical Sciences Department, Medical Laboratory Department, Zarqa University, Zarqa, Jordan.

For correspondence:-  Maissa Shawagfeh   Email: mtash48@bau.edu.jo

Received: 1 March 2026        Accepted: 15 July 2026        Published: 31 July 2026

Citation: Shawagfeh MT, Shawagfeh MT, Yousef IF. Sodium, potassium and calcium ions in diabetic patients' serum and their correlation with glycaemic control in Jordanian patients: A cross-sectional study. Trop J Pharm Res 2026; 25(7):1003-1006 doi: https://dx.doi.org/10.4314/tjpr.v25i7.13

© 2026 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..

Abstract

Purpose: To assess the correlation among calcium (Ca+2), potassium (K+), and sodium (Na+) electrolyte disturbances with glycaemic control in Jordanian diabetic patients in a cross-sectional study. Methods: The data of 236 patients were enrolled in the study, of which 120 were diabetic patients, while the remaining 116 non-diabetic patients were used as controls. Data were selected from different departments of King Talal Military Hospital in Mafraq, Jordan. Fasting blood glucose, Na+, K+, and Ca+2 were analyzed by the ROCHE module Cobas analyzer using ROCHE kits in the hospital laboratories. Results: Diabetic patients were of mean age of (61.1 ± 15.9) years. Sodium (Na+) showed a significant negative correlation, Calcium (Ca+2) showed an insignificant negative correlation, while Potassium (K+) showed a positive association with fasting blood glucose. Conclusion: The study demonstrates that there are differences between electrolytes (Na+, K+, Ca+2) in diabetic patients compared to non-diabetic patients, suggesting that monitoring them will help in disease management.

Keywords: Calcium, Diabetic patients, Electrolyte disturbance, Fasting glucose, Potassium, Sodium

Impact Factor
Thompson Reuters (ISI): 0.6 (2023)
H-5 index (Google Scholar): 49 (2023)

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