Evren Algın-Yapar1 
,
Özge İnal2
For correspondence:- Evren Algın-Yapar Email: evren.yapar@yahoo.com Tel:+9005323825686
Received: 23 July 2012 Accepted: 15 February 2014 Published: 24 March 2014
Citation: Algın-Yapar E, İnal &. Transdermal Spray in Hormone Delivery. Trop J Pharm Res 2014; 13(3):469-474 doi: 10.4314/tjpr.v13i3.23
© 2014 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..
This review examines advances in hormone delivery, particularly using transdermal spray. Transdermal gels, emulsions, patches, subcutaneous implants and sprays have been developed for transdermal hormone therapy in recent years. Transdermal sprays, in their general form of metered-dose transdermal spray, possess major advantages such as enhanced passive transdermal drug delivery with little or no skin irritations, improved cosmetic acceptability, dose flexibility, uniform distribution on the application site and ease of manufacture, and have thus assumed significant importance in hormone delivery. Estradiol, nestrone, testosterone and hydrocortisone aceponate are some of the drugs prepared as metered-dose transdermal spray. Results from recent surveys indicate that there is a market for the delivery system and ongoing development of transdermal sprays for hormone delivery.
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