Ji Hyung Kim1,
Hwa Jun Cha2 
For correspondence:- Hwa Cha Email: hjcha@osan.ac.kr
Accepted: 26 May 2022 Published: 30 June 2022
Citation: Kim JH, Cha HJ. Lactobacillus Kimchicus-fermented Ficus caria fruits and leaves extract as an inhibitor of ?-MSH-mediated melanogenesis in B16F10 mouse melanoma cells. Trop J Pharm Res 2022; 21(6):1189-1193 doi: 10.4314/tjpr.v21i6.8
© 2022 The authors.
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Purpose: To explore the anti-melanogenetic effects of Lactobacillus Kimchicus-fermented Ficus caria fruits and leaves extracts (KFFE) in B16F10 mouse melanoma cells.
Methods: The anti-melanogenetic effects of Lactobacillus Kimchicus-fermented Ficus caria fruit and leaf extracts (KFFE) were assessed using melanin contents assay and tyrosinase ex
Results: The KFFE reduced α-MSH-mediated melanin synthesis in B16F10 mouse melanoma cells, while the tyrosinase mRNA ex
Conclusion: KFFE functions to repress melanin synthesis and thus, can potentially be used as a cosmetic ingredient.
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