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Review Article | OPEN ACCESS

Phytobotanical and compositional profiling of Pereskia aculeata and optimization of extraction processes for its bioactive fractions

Obioma R Emeka-Obi1 , Chekwube A Ezegbe2, Joel O Onoja3,4, Ezinne C Okorafor5

1Department of Haematology, School of Basic Clinical Sciences, College of Medicine, Federal University of Technology, Owerri, Imo State; 2Department of Pharmaceutical Technology and Industrial Pharmacy, University of Nigeria, Nsukka; 3Department of Pharmacognosy and Environmental Medicine, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Nigeria; 4Center of Excellence in Natural Products Chemistry, Department of Chemistry, Faculty of Sciences, Chulalongkorn University, Bangkok 10330, Thailand; 5Department of Pharmacology, School of Basic Clinical Sciences, College of Medicine, Federal University of Technology, Owerri, Imo State, Nigeria.

For correspondence:-  Obioma Emeka-Obi   Email: raluchukwu.emeka-obi@futo.edu.ng

Received: 24 March 2026        Accepted: 19 September 2026        Published: 30 September 2026

Citation: Emeka-Obi OR, Ezegbe CA, Onoja JO, Okorafor EC. Phytobotanical and compositional profiling of Pereskia aculeata and optimization of extraction processes for its bioactive fractions. Trop J Pharm Res 2026; 25(9):1323-1327 doi: 10.4314/tjpr.v25i9.15

© 2026 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..

Abstract

Pereskia aculeata (Cactaceae) is a well-known plant species commonly found and used in South America, due to its therapeutic and pharmacological properties. This review consolidates existing knowledge on Pereskia aculeata phytobotanical, chemical composition and extraction processes. The phytochemical analysis revealed the presence of flavonoids, alkaloids and terpenoids, which are very essential for the plant’s bioactivity. The phytobotanical and compositional profiling of Pereskia aculeata and optimization of extraction processes for its bioactive fractions have been documented. Evidence abounds on the traditional uses of this plant in pain management, wounds and inflammatory conditions. This review underscores Pereskia aculeata potential for developing phytochemical constituents that could be used in the treatment of various diseases

Keywords: Pereskia aculeata, Phytobotanical properties, Phytochemical analysis, Therapeutics

Impact Factor
Thompson Reuters (ISI): 0.6 (2023)
H-5 index (Google Scholar): 49 (2023)

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