Tropical Journal of Pharmaceutical Research

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ISSN: 1596-5996 (print); 1596-9827 (electronic)-

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Research Article

Effect of Standardized Decoction of Nigella sativa Seed, Hemidesmus indicus Root and Smilax glabra Rhizome on the Expression of p53 and p21 Genes in Human Hepatoma Cells (HepG2) and Mouse Liver with Chemically-Induced Hepatocarcinogenesis

Sameera R Samarakoon, Ira Thabrew, Prasanna B Galhena and Kamani H Tennekoon

¹Institute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, 90, Cumarathunga Munidasa Mawatha, Colombo 3, ²Department of Biochemistry and Clinical Chemistry, Faculty of Medicine, University of Kelaniya, Thalagolla Road, Ragama, Sri Lanka.

*For correspondence: Email: ranganath148@yahoo.com Tel: +94 112 552 528; Fax: +94 112 552 529

Received: 10 May 2011 Revised accepted: 11 December 2011

Tropical Journal of Pharmaceutical Research, February 2012; 11(1): 51-61

http://dx.doi.org/10.4314/tjpr.v11i1.7

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