Current
Knowledge on Microarray Technology - An Overview
Chitrala
Kumaraswamy Naidu
and
Yeguvapalli Suneetha*
Department of Zoology, Sri Venkateswara University,
Tirupati -517502, India.
*For correspondence:
Email:
ysuneethareddy4@gmail.com Tel: +91
9985563644
Received: 19 April
2011 Revised
accepted: 19 December 2011
Tropical Journal of
Pharmaceutical Research, February 2012; 11(1): 153-164
http://dx.doi.org/10.4314/tjpr.v11i1.20
Abstract
The completion of whole
genome sequencing projects has led to a rapid increase
in the availability of genetic information. In the field
of transcriptomics, the emergence of microarray-based
technologies and the design of DNA biochips allow
high-throughput studies of RNA expression in cell and
tissue at a given moment. It has emerged as one of the
most important technology in the field of molecular
biology and transcriptomics. Arrays of oligonucleotide
or DNA sequences are being used for genome-wide
genotyping and expression profiling, and several
potential clinical applications have begun to emerge as
our understanding of these techniques and the data they
generate improves. From its emergence to date, several
database, software and technology updates have been
developed in the field of microarray technology. This
paper reviews basics and updates of each microarray
technology and serves to introduce newly compiled
resources that will provide specialist information in
this area.
Keywords:
Microarray, Databases, cDNA array,
Oligonucleotide array.
