Sodium Carboxymethyl Chitosan as a Fixative for Eau de
Cologne
Surawut
Wannaruemon1, 2 Ampa Jimtaisong1*
and Pornchai Rachtananpun3,4
1School of
Cosmetic Science, Mae Fah Luang University, 333 Moo1,
Thasud, Muang, Chiang Rai, 57100, 2Bangkok
Perfumery, Co., Ltd., Muang, Nonthaburi 11000, 3Division
of Packaging Technology, Faculty of Agro-Industry,
Chiang Mai University, Muang, Chiang Mai 50100, 4Materials
Science Research Center, Faculty of Science, Chiang Mai
University 50200, Thailand
*For correspondence: E-mail:
ampa@mfu.ac.th
Tel:+6653916843; Fax: +6653916831
Received: 28 March
2012
Revised accepted:
12 December 2012
Tropical
Journal of Pharmaceutical Research, February 2013;
12(1): 45-49
http://dx.doi.org/10.4314/tjpr.v12i1.8
Abstract
Purpose: To study the
characteristics of sodium carboxymethyl chitosan (SCM-chitosan)
as a fixative for eau de cologne product.
Methods: SCM-chitosan was
prepared by carboxymethylation reaction of chitosan with
monochloroacetic acid. The solubility of SCM-chitosan
was investigated in water and ethanol. Sixteen perfume
compounds which consisted of four chemical types -
alcohols, ketones, aldehydes and ethers - were selected
for eau de cologne preparation. The turbidity of the
products prepared was monitored over 21-day aging
period. Those showing no turbidity were selected for
fixative studies with SCM-chitosan. The fixative effect
of SCM-chitosan was evaluated by head space gas
chromatography at different temperatures (25, 35 and 53
°C).
Results: The prepared
SCM-chitosan was soluble in water but insoluble in
ethanol. The optimum ratio between water and ethanol
that could completely dissolve 0.1 % SCM-chitosan was
2:3 v/v. SCM-chitosan showed significant fixative effect
(3.9 - 92.2 %) on p-cresyl methyl ether (10 % in
dipropyleneglycol). Fixative efficiency increased from
3.9 % at 25°C to 42.1 % at 35 °C and 92.2 % at 53 °C.
However, products containing benzyl alcohol, ethyl
acetoacetate and 94085 floral-fruity showed
precipitation after 21 days.
Conclusion: The results
obtained indicate that SCM-chitosan could be used as a
potential fixative for eau de cologne products.
Keywords: Biopolymer,
carboxymethyl chitosan, cologne, fixative, perfume
.
