Incidence and Antibiotic
Susceptibility Pattern of Bacterial Isolates from Wound
Infections in a Tertiary Hospital in Nigeria
Aisha Mohammed, Gbonjubola
O Adeshina* and Yakubu K Ibrahim
Department of Pharmaceutics
and Pharmaceutical Microbiology, Ahmadu Bello
University, Zaria, Nigeria
*For
correspondence: Email:
dotunkele@yahoo.com
Tel: +234-8037880000
Received: 18 October 2012
Revised accepted: 17 June
2013
Tropical Journal of
Pharmaceutical Research, August 2013; 12(4):
617-621
http://dx.doi.org/10.4314/tjpr.v12i4.26
Abstract
Purpose: To investigate the incidence of different
bacteria isolates in 150 wound infections
in Aminu Kano Teaching
Hospital, Kano, Nigeria
and
their antibacterial susceptibility patterns.
Methods: Wound swab samples were
collected from general culture bench of the Microbiology
Department, after obtaining consent from the hospital’s
Medical Advisory Committee, and cultured for bacterial
isolates. The isolates were characterized and identified
by standard microbiological methods. Antibiotic
susceptibility testing was carried out using
Kirby-Bauer-CLSI modified Disc Agar Diffusion technique.
Results: Out of the 150 specimens
collected, 82 % were infected with bacteria made up
predominantl of Staphylococcus aureus (22 %),
Pseudomonas aeruginosa (19.9 %), Citrobacter spp (15 %),
Escherichia coli (14.7 %) and Proteus mirabilis (14.5
%). In vitro antibiotic susceptibility tests showed that
Pseudomonas aeruginosa was susceptible to ceftazidime,
ciprofloxacin and gentamicin while the enteric bacteria
were generally more resistant to ceftazidime, gentamicin
and ciprofloxacin.
Conclusion: The findings show that
there is a high rate of wound infection in Kano, Nigeria
and that antibiotic-resistant bacteria are present in
the wound sites.
Keywords: Wound
infection ,
Antibiotic, Susceptibility, Bacterial
resistance
