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Original Research Article
Determination of Chemical
Constituents of the Marine Pulmonate Slug,
Paraoncidium reevesii
Bian-Na Sun1,2,
He-Ding Shen1*, Hong-Xi Wu2,3, Li-Xiang
Yao1, Zhi-Qing Cheng1 and Ya Diao1
1Key Laboratory of Exploration
and Utilization of Aquatic Genetic Resources, Ministry
of Education, Shanghai Ocean University, Shanghai
201306, 2Zhejiang Mariculture Research
Institute, 3Zhejiang Key Lab of Exploitation
and Preservation of Coastal Bio-Resource, Wenzhou
325005, China
*For correspondence:
Email:
hdshen@shou.edu.cn; Tel: + 86
21 61900446; Fax: + 86 21 61900405
Received: 16 May 2014
Revised accepted: 29
October 2014
Tropical
Journal of Pharmaceutical Research, December 2014;
13(12):
2071-2074
http://dx.doi.org/10.4314/tjpr.v13i12.18
Abstract
Purpose: To isolate and identify the
chemical components of Paraoncidium reevesii.
Methods: Silica gel column
chromatography was used to isolate the components from
petroleum ether and ethyl acetate fractions of the
acetone extract, and the structures of the compounds
were derived from 1H-nuclear magnetic
resonance (1H-NMR), 13C-nuclear
magnetic resonance (13C-NMR) and mass
spectrometry (MS) analyses and also with the aid of
literature data for authenticated samples.
Results: Cholesterol (1),
baconipyrone D (2), chimyl alcohol (3), batyl alcohol
(4), α-monpalmitin (5), stearic acid (6),
3-indolecarboxylic acid (7), uracil (8), thymine (9),
uridine (10), thymidine (11) were isolated from the
marine slug (Paraoncidium reevesii).
Conclusion: All the isolated compounds
are being reported here for Paraoncidium reevesii for
the first time. The results provide base data for
further study of the Onchidiidae as a Chinese
traditional remedy for asthma and athlete’s foot.
Keywords: Mollusk, Paraoncidium
reevesii, Baconipyrone D, Batyl alcohol, Chimyl alcohol
Onchidiidae, Marine Pulmonate, Slug, Asthma, Athlete’s
foot |
