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Original
Research Article
Studies on
Wound healing properties of Quercus
Infectoria
SP Umachigia, KN Jayaveerab, CK
Ashok Kumarc, GS Kumard, BM
Vrushabendra swamye, and DV Kishore Kumarf
aDepartment
of Pharmaceutics, dDepartment of
Pharmacognosy, eDepartment of Pharmacology,
fDepartment of Chemistry, Rural College of
Pharmacy, D.S.Road, Devanahalli-562110 Karnataka, India.
bDepartment
of Chemistry, Jawaharlal Nehru Technological University
College of Engineering, Ananthpur- 01, Andhra Pradesh,
India,
cDepartment
of Pharmacognosy, Sree Vidyanikethan, College of
Pharmacy, A.Rangamepeta, Chittoor Dist, Andhra Pradesh,
India.
Tropical
Journal of Pharmaceutical Research, March
2008; 7(1):
913-919
Abstract
Purpose: The aim of the present study
was to investigate the wound healing activity of the
selected Indian medicinal plant Quercus infectoria.
Method: Ethanol extract of the
shade-dried leaves of Quercus infectoria was studied for
its effect on wound healing in rats, using incision,
excision and dead-space wound models, at two different
dose levels of 400 and 800 mg/kg.
Result: The plant showed a definite,
positive effect on wound healing, with a significant
increase in the levels of the antioxidant enzymes,
superoxide dismutase and catalase, in the granuloma
tissue.
Conclusion: The efficacy of this plant
in wound healing may be due to its action on antioxidant
enzymes, thereby justifying the traditional claim.
Key words: Quercus infectoria, wound healing,
superoxide, catalase |
