Evaluation of the Antibacterial Activity of 14 Medicinal
Plants in Côte d’Ivoire
GEK Bolou1, I Bagré1*,
K Ouattara1 and AJ Djaman1,2
1Biochemical
Pharmacodynamy Laboratory, Biosciences Department,
Cocody University, Abidgan;
2Biochemical
Laboratory of Pasteur Institute of Cote d’Ivoire,
Abidgan.
For correspondence:
E-mail:
bagrefreefr@yahoo.fr Tél:
+225-(0)8008901
Received: 10 July
2010 Revised
accepted: 24 April 2011
Tropical
Journal of Pharmaceutical Research, June 2011;
10(3):
335-340
doi:
10.4314/tjpr.v10i3.3
Abstract
Purpose:
To evaluate the
antibacterial potentials of fourteen ethnobotanically
selected plants traditionally used in different parts of
Côte d’Ivoire for the treatment of typhoid fever and
gastrointestinal disorders.
Method:
The antimicrobial
activity of the extracts of the plant was tested against
a collection strain of
Salmonella
typhimurium, a clinical strain of
Salmonella typhi and Pseudomonas
aeruginosa by macrobroth dilution method. Minimum
inhibitory concentration (MIC) and minimum bactericidal
concentration (MBC) were determined.
Results:
All the plants had
bactericidal activity against at least one of the test
microorganisms with both MIC and MBC ranging from 2.5 to
> 80 mg/ml.
Among the plant extracts, Terminalia glaucescens. (Combretaceae)
Bersama abyssinica subsp. paullinioides (Melianthaceae )
and Abrus precatorius (Fabaceae) showed the most
promising broad spectrum antibacterial properties,
inhibiting all of the strains tested, especially S.
Typhi and P. aeruginosa, with MBC ranging from 2.5 to 5
mg/ml.
Conclusion:
The findings
provide support for the use of these plants in
traditional medicine for treatment of typhoid fever and
gastrointestinal disorders, and are thus, potential
sources of drugs that would need to be subjected to
further studies.
Keywords:
Antimicrobial
activity, Ivorian medicinal plants, MIC, MBC.
