Tropical Journal of Pharmaceutical Research

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Review Article

Pharmacological Applications of Quercetin and its Derivatives: A Short Review

Aneela Maalik¹*, Farhan A. Khan¹, Amara Mumtaz¹, Adeem Mehmood¹, Saira Azhar², Muhammad Atif¹, Sabiha Karim³, Yasir Altaf¹ and Imran Tariq³

1Department of Chemistry, 2Department of Pharmacy, COMSATS Institute of Information Technology, Abbottabad-22060, KPK, 3University College of Pharmacy, University of Punjab, Lahore, Pakistan

*For correspondence: Email: aneelamaalik@ciit.net.pk; Tel: +92 333 549 0834; Fax: +92 992 383441

Received: 18 June 2014 Revised accepted: 7 August 2014

Tropical Journal of Pharmaceutical Research, September 2014; 13(9): 1561-1566

http://dx.doi.org/10.4314/tjpr.v13i9.26

Abstract

Quercetin (3,3ʹ,4ʹ,5,7-pentahydroxyl-flavone) is a flavonol, and it belongs to a class of plant secondary metabolites known as flavonoids. It is present in man’s daily diet and is known for biological activities such as antioxidant, antiviral, anticancer, antimicrobial, anti-inflammatory and many more. Quercetin has been reported for its antioxidant and antiviral applications, hence, it is not only used as such but also its various derivatized forms have potentials for development into drugs for the treatment of diseases caused by oxidative stress and lethal viruses.

Keywords: Quercetin, Antioxidant, Pharmacological, Anticancer, Antimicrobial, Antiviral, Hepatoprotective